Tidal Volume Dependence on the Ventilatory Frequency and Alveolar Compliance in HFOV

Authors: Martin Rožánek, Zuzana Horáková, Barbora Padertová, Jakub Ráfl, Karel Roubík

Citation

Rozanek M, Horakova Z, Padertova B, Rafl J, Roubik K. Tidal Volume Dependence on the Ventilatory Frequency and Alveolar Compliance in HFOV. Biomedical Engineering/Biomedizinische Technik. 2013; 58 (Supplement 1):000010151520134329.

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Abstract

High frequency oscillatory ventilation has limited possibility of monitoring of intrapulmonary parameters. We have measured tidal volume during high frequency oscillatory ventilation by external monitor. The experimental circuit consisted of ventilator 3100 with its patient circuit, lung simulator 5600i and monitor Florian for measuring of tidal volume. Tidal volume was measured for different values of alveolar compliance that were set on the lung simulator. Measurement was repeated for ventilatory frequencies 3, 5, 7 and 10 Hz. Ventilatory parameters were held constant during the experiment. We have found that change of alveolar compliance has minimal effect on the delivered tidal volume.

References

[1] Pachl J, Roubík K, Waldauf P, Fric M, Zábrodský V.: Normocapnic High-frequency oscillatory ventilation affects differently extrapulmonary and pulmonary forms of acute respiratory distress syndrome in adults, Physiological Research, vol. 55, pp. 15-24, 2006.
[2] Gattinoni L, Pelosi P, Suter PM, et al.: Acute respiratory distress syndrome caused by pulmonary and extrapulmonary disease. Different syndromes?, Am J Respir Crit Care Med, vol. 158, 99. 3-11, 1998.
[3] Pelosi P, D’Onofrio D, Chiumello D, et al.: Pulmonary and extrapulmonary acute respiratory distress syndrome are different, Eur Respir J, vol. 22, pp. 48s–56s, 2003.
[4] Rozanek M, Roubík K, Horáková Z.: Simulation of the Different Respiratory Mechanics Effect upon the Efficiency of Artificial Lung Ventilation Using Mathematical Model of the Respiratory System, in: World Congress on Medical Physics and Biomedical Engineering, Munich, Germany, pp. 1674-1676, 2009, ISBN 978-3-642-03881-5.
[5] Chan KPW, Stewart TE, Mehta S.: High-frequency oscillatory ventilation for adult patients with ARDS, Chest, vol. 131, pp. 1907-1916, 2007.
[6] Fessler HE, Derdak S, Ferguson ND, et al.: A protocol for high-frequency oscillatory ventilation in adults: Results from a roundtable discussion. Crit Care Med, vol. 35, pp. 1649-1654, 2007.
[7] Sud S, Sud M, Friedrich JO, Meade MO, Ferguson ND, Wunsch H, Adhikari NK.: High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and metaanalysis, BMJ, vol. 18, p. c2327, May 2010.