Authors: Martin Rožánek, Zuzana Horáková, Ondřej Čadek, Martin Kučera, Karel Roubík


Rozanek, M., Horakova, Z., Cadek, O., Kucera, M. and Roubik, K., 2012. Damping of the dynamic pressure amplitude in the ventilatory circuit during high-frequency oscillatory ventilation. Biomedical Engineering/Biomedizinische Technik, 57(SI-1 Track-O), pp.53-56.

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Published in Biomedical Engineering / Biomedizinische Technik


The study deals with experimental measuring of attenuation of dynamic pressure during high-frequency oscillatory ven-tilation. The experimental circuit consists of high-frequency oscillatory ventilator Sensormedics 3100 B, patient circuit and lung model 5600i. Different values of the flow resistance and alveolar compliance were modelled during the ex-perimental measurement. The ventilatory parameters of the oscillatory ventilator were constant during whole measure-ment. We confirm a decrease of the amplitude of the pressure swings in the alveolar space during high-frequency oscilla-tory ventilation. Dependence on the mechanical properties of the respiratory system was found.


[1] Ferguson N.D., Frutos-Vivar F., Esteban A. Airway Pressures, Tidal Volumes, and Mortality in Patients With Acute Respiratory Distress Syndrome. Crit Care Med ;33(1):21–30, 2005
[2] Chan K.P.W., Stewart E., Mehta S. High-Frequency Oscillatory Ventilation for Adult Patients with ARDS. Chest;131(6):1907-1916, 2007
[3] Gerstmann D.R., Fouke J.M., Winter D.C., Proximal, Tracheal, and Alveolar Pressures during High-Frequency Oscillatory Ventilation in a Normal Rabbit Model. Pediatr Res; 28(4):367-73, 1990
[4] Allen J.L., Frantz I.D. 3rd, Fredberg J.J. Regional Al-veolar Pressure during Periodic Flow. Dual Manifesta-tions of Gas Inertia. J Clin Invest; 76(2):620-9, 1985
[5] Frantz I.D. 3rd, Close R.H. Alveolar Pressure Swings during High-Frequency Ventilation in Rabbits. Pediatr Res. 19(2):162-6, 1985
[6] Rozanek M., Roubik K. Influence of the Changes in Pulmonary Mechanics upon the Suitability of Artifi-cial Lung Ventilation Strategy. Biomedical Engineer-ing, Biomedical engineering; 474-477, 2004
[7] van Genderingen H.R., Versprille A., Leenhoven T., Markhorst D.G., van Vught A.J., Heethaar R.M. Re-duction of Oscillatory Pressure along the Endotracheal Tube is Indicative for Maximal Respiratory Compli-ance during High-Frequency Oscillatory Ventilation: a Mathematical Model Study. Pediatr Pulmonol; 31(6):458-63, 2001
[8] Pelosi P., D’Onofrio D., Chiumello D., Gattinoni L., et. al. Pulmonary and Extrapulmonary Acute Respira-tory Distress Syndrome are Different; Eur Respir J; 22:48S–56S, 2003
[9] Gattinoni L., Pelosi P., Suter P.M., et. al. Acute Respi-ratory Distress Syndrome Caused by Pulmonary and Extrapulmonary Disease. Am J Respir Crit Care Med; 158:3–11, 1998
[10] Pachl J., Roubík K., Waldauf P., Fric M., Zábrodský V. Normocapnic High-frequency Oscillatory Ventila-tion Affects Differently Extrapulmonary and Pulmo-nary Forms of Acute Respiratory Distress Syndrome in Adults; Physiological Research; 55 (1), 15–24, 2005
[11] Stachow R. High-Frequency Ventilation, Basics and Practical Application; Allgemeines Krankenhaus, Heidberg, Hamburg, 1995
[12] Pillow J.J., Sly P.D., Hantos Z., Bates J.H. Depend-ence of Intrapulmonary Pressure Amplitudes on Res-piratory Mechanics during High-Frequency Oscilla-tory Ventilation in Preterm Lambs. Pediatr Res; 52(4):538-44, 2002