Authors: Martin Rozanek, Karel Roubik, Zuzana Horakova


Rozanek, M., Roubik, K., & Horakova, Z. (2009). Simulation of the different respiratory mechanics effect upon the efficiency of artificial lung ventilation using mathematical model of the respiratory system. In World Congress on Medical Physics and Biomedical Engineering, September 7-12, 2009, Munich, Germany (pp. 1674-1676). Springer, Berlin, Heidelberg.

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The study deals with design and implementation of a mathematical model of the human respiratory system according to its anatomical structure. The model is designed in order to simulate distribution of important intrapulmonary parameters along the bronchial tree such as pressure amplitude, tidal volume and regional mechanical lung properties. The model is based on the lung morphology and electro-acoustic analogy is used to design the model. The model allows changing the mechanical parameters of the airways and alveolar compliance. conducted simulations suggest that efficiency of artificial lung ventilation is significantly dependent on the mechanical properties of lungs.


1.Weibel E R (1963) Morphometry of the human lung. Springer-Verlag, Berlin.
2.Shields T W, LoCicero J, Ponn R B (2000) General Thoracic Surgery. 5th edition, Lippincott Williams & Wilkins, Philadelphia Jongh F H C (1995) Ventilation modelling of the human lung.Delft university of technology, Delft.
4.Škvor Z (2001) Akustika a elektroakustika. Academy of Science,Prague.
5.West J B (1992) Pulmonary Pathophysiology – the essentials. 4th edition, Williams & Wilkins, Baltimore
6.Pelosi P, D’Onofrio D, Chiumello D, et al. (2003) Pulmonary andextrapulmonary acute respiratory distress syndrome are different. EurRespir J 22:48S-56S.